Today is day one of James’ journey with a clinical trial. Every appointment, blood draw, poke and stick that has led to this day has been in preparation for not part of.
However, at 4:05pm on 9/12/17, James started his very first infusion of a drug (Atezolizumab) that we hope boosts his immune system to recognize that those stupid mucin cells are bad, very bad and start to fight them!
It is also Day 1 of chemotherapy. James has never had Chemo outside of HIPEC, during his surgery. Today he begins cycle 1 (21 days) of cobimentinib.
Can I just tell you how much I hate this! I often wish I could trade places with him. However, I am so grateful for his courage to try this and step into the unknown just in hopes that it may extend his life or that of someone else!! He is my hero!!
One other bit of news, his genetic testing came back (you remember that genetic testing that I have begged for for years). James has the KRAS mutation (not KRAS Wild). What does this mean? They know for sure what Chemo drugs would not work for him BUT in other clinical studies (colon cancer specifically) they have seen good results with people on cobimentinib and that have the KRAS mutation. Apparently, cobimentinib blocks the KRAS mutation!
We are 30 minutes in and James is doing great! His spirits are up, he is not having any issues and his stinking blood pressure is 114/65!! I tell you, this man is as healthy as a horse if it weren’t for PMP!
So.. prayer warriors! Get to it!! 🎗💛